Ling, Zhihao; Brockmöller, Thomas; Baldwin, Ian T.; Xu, Shuqing: Evolution of Alternative Splicing in Eudicots
Inhalt
- Read Mapping, Transcripts Assembly, and Abundance Estimation
- AS Detection
- Identification of Conserved Exon–Exon Junctions (EEJs) and AS
- Identification of AS Events That Generate Premature Termination Codons (PTC)
- One-to-One Orthologous Gene Identifications and Gene Family Size Estimation
- Correlation and Clustering
- Identification of Possible Alternative Splice Sites (SS) and Regulatory Sequences
- Deciphering the Splicing Codes and AS Conservation Using a Deep Learning Algorithm
- Results
- Genome-Wide AS Patterns Are Species-Specific in Plants
- Massive Gains and Losses of AS Among Different Species
- The AS Events That Result in PTC-Containing Transcripts Are Likely More Conserved Than Others
- Mechanisms Involved in Determining AS Are Overall Conserved Among Different Plant Species
- Changes in AS Determinants Contributed to the Divergence of AS in Plants
- Discussion
- Conclusion
- Author Contributions
- Funding
- Acknowledgments
- Supplementary Material
- References