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Evolution of Alternative Splicing in Eudicots
Results
Mechanisms Involved in Determining AS Are Overall Conserved Among Different Plant[...]
Read Mapping, Transcripts Assembly, and Abundance Estimation
AS Detection
Identification of Conserved Exon–Exon Junctions (EEJs) and AS
Identification of AS Events That Generate Premature Termination Codons (PTC)
One-to-One Orthologous Gene Identifications and Gene Family Size Estimation
Correlation and Clustering
Identification of Possible Alternative Splice Sites (SS) and Regulatory Sequences
Deciphering the Splicing Codes and AS Conservation Using a Deep Learning Algorithm
Results
Genome-Wide AS Patterns Are Species-Specific in Plants
Massive Gains and Losses of AS Among Different Species
The AS Events That Result in PTC-Containing Transcripts Are Likely More Conserved Than Others
Mechanisms Involved in Determining AS Are Overall Conserved Among Different Plant Species
Changes in AS Determinants Contributed to the Divergence of AS in Plants
Discussion
Conclusion
Author Contributions
Funding
Acknowledgments
Supplementary Material
References
Aufsatz in einer Zeitschrift
Evolution of Alternative Splicing in Eudicots
Entstehung
12.6.2019
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