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Benchmarking tools for the alignment of functional noncoding DNA
Results
Comparative analysis of genomic alignment tools
Coverage and sensitivity in constrained sequences
Background
Results
Properties of noncoding DNA in Drosophila
Estimates of divergence between taxa used in comparative genomics
Simulating noncoding sequence evolution
Table 1
Characterization of simulation outputs
Comparative analysis of genomic alignment tools
Coverage
Sensitivity
Coverage and sensitivity in constrained sequences
Specificity to detect constrained sequences
Discussion
Conclusions
Methods
Modelling input sequences for the simulation of Drosophila noncoding DNA
Divergence estimates in flies, worms and mammals
Simulating noncoding sequence divergence
Tools for aligning noncoding DNA
Alignment performance measures
Authors' contributions
Acknowledgements
Acknowledgements
References
Aufsatz in einer Zeitschrift
Benchmarking tools for the alignment of functional noncoding DNA
Entstehung
2004
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