Dobrindt, Ulrich; Wami, Haleluya T.; Schmidt-Wieland, Torsten; Bertsch, Daniela; Oberdorfer, Klaus; Hof, Herbert: Compared with Cotrimoxazole Nitroxoline Seems to Be a Better Option for the Treatment and Prophylaxis of Urinary Tract Infections Caused by Multidrug-Resistant [...]
Inhalt
- Results
- Prevalence of MDR among E. coli Isolates from Urine Samples
- Overall Activity of Nitroxoline against Multiresistant Uropathogens
- Parallel Resistance to Cotrimoxazole and 3rd Generation Cephalosporins, Ciprofloxacin and MDR Strains of E. coli
- Co-Localisation of Transferable Resistance to Cotrimoxazole, ESBL and Quinolones
- Discussion
- Co-Localisation of Transferable Resistance to Cotrimoxazole, ESBL and Quinolones
- Parallel Resistance Due to Accumulation of Resistance Determinants on Mobile Genetic Elements
- Materials and Methods
- Urine Culture Analysis and Antibiotic Susceptibility Testing
- Genome Sequencing
- Annotation and Strain Typing
- Analysis of Co-Occurrence of Cotrimoxazole and Other Antimicrobial Resistance Genes in Bacterial Genomes
- Conclusions
- References