Rumpf, Christine; Lange, Jonas; Schwartbeck, Bianca; Waschkau, Bianca; Kahl, Barbara C.: Staphylococcus aureus and Cystic Fibrosis—A Close Relationship. What Can We Learn from Sequencing Studies?
Inhalt
- Adaptation to CF Airways
- Clinical Impact
- S. aureus—Fundamentals of Pathogenicity
- S. aureus Virulence Genome
- Role of Agr in Virulence Gene Regulation Via Quorum Sensing
- Role of Horizontal Gene Transfer in the Spread of Virulence Genes
- Impact of Varying Genotypes and Single Genes on S. aureus Pathogenicity
- Genotyping of S. aureus in Cystic Fibrosis
- Adaptation of S. aureus towards Persistence in Cystic Fibrosis Using WGS
- S. aureus Population Dynamics in CF
- MRSA in Cystic Fibrosis—Antibiotic Resistance, Persistence and Patho-Adaptation
- Biofilm Formation—An Adaptive Mechanism of S. aureus in Cystic Fibrosis
- Summary and Conclusions
- References