Michel, Philipp; Kronenberg, Daniel; Neu, Gertje; Stolberg-Stolberg, Josef; Frank, Andre; Pap, Thomas; Langer, Martin Franz; Fehr, Michael; Raschke, Michael J.; Stange, Richard: Microsurgical reconstruction affects the outcome in a translational mouse model for Achilles tendon healing
Inhalt
- Methods
- Animals
- Study design
- Groups: Part 1
- Groups: Part 2
- Groups: Part 3
- Step-by-step description of the operation technique
- Histological investigations
- Micro-CT and bone volume measurement
- Biomechanical testing
- Statistical analysis
- Results
- 1
- 2
- Partial loosening of the immobilization cerclage led to increasing movement in the UAJ during the healing period
- Significant learning curve for the operation time
- Histologic analysis shows a maturation of collagen fibres within 6 weeks
- HOs are detectable after 4 weeks and show a progressive bone volume 16 weeks postoperatively
- Tendon biomechanics are altered in the operated tendons and remain inferior after 6 weeks
- 3
- Discussion
- Funding
- Conflict of Interest
- Author contributions
- Acknowledgements
- Appendix A. Supplementary data
- References