Ateacha, Derick Nzogoa: Development and optimisation of mass spectrometric techniques for the analysis of antimalarial pharmaceuticalsEntwicklung und Optimierung von massenspektrometrischen Techniken zur Analyse von Antimalaria-Arzneimittel. 2018
Inhalt
- Abstract
- Kurzfassung
- Table of Content
- Chapter 1 - Introduction and Scope of the Thesis
- 1.1 Background
- 1.2 Scope of the thesis
- 1.3 State-of-the-art in mass spectrometric-based methods for antimalarial analysis
- Chapter 2 - Fundamental Study on High-Temperature - High Performance Liquid Chromatography Mass Spectrometry for Pharmaceutical Analysis
- Abstract
- 2.1 Introduction
- 2.2 Experimental
- 2.3 Results and Discussion
- 2.4 Conclusion
- Appendix for Chapter 2
- Chapter 3 - Optimisation and Application of High-Temperature High Performance Liquid Chromatography Mass Spectrometry for the Analysis of Cinchona Alkaloids
- Abstract
- 3.2 Introduction
- 3.3 Experimental
- 3.4 Results and Discussion
- 3.5 Conclusion
- Appendix for Chapter 3
- Chapter 4 - Analysis of Artemisinin-Based Antimalarial Pharmaceuticals by High-Temperature High Performance Liquid Chromatography Mass Spectrometry
- Abstract
- 4.1 Introduction
- 4.2 Experimental
- 4.3 Results and Discussion
- 4.4 Conclusion
- Appendix for Chapter 4
- Chapter 5 - Direct Analysis of Alkaloids in Natural Cinchona Bark and Commercial Extracts using Time-of-Flight Secondary Ion Mass Spectrometry
- Abstract
- 5.1 Introduction
- 5.2 Experimental Section
- 5.3 Results and Discussion
- 5.4 Conclusion and Future Perspectives
- Appendix for Chapter 5
- Chapter 6 - Rapid Qualitative Screening of Antimalarials Using Low-Temperature Plasma Desorption/Ionisation Orbitrap Mass Spectrometry
- Abstract
- 6.1 Introduction
- 6.2 Experimental Section
- 6.3 Results and Discussions
- 6.4 Conclusion
- Appendix for Chapter 6
- Chapter 7 - Concluding Remarks and Future Perspectives
- References
- List of Figures
- List of Tables
- List of Abbreviations and Symbols
- Acknowledgements
- Curriculum Vitae
- List of Publications