Petri, Christian: Synthesis and characterization of novel photocrosslinkable poly(2-oxazoline)-based hydrogel systems for the application as biosensor matrix. 2018
Inhalt
- Acknowledgements
- Zusammenfassung
- Summary
- List of Abbreviations
- Contents
- 1. Introduction
- 2. Theory
- 2.1 Oxazolines and Poly(2-oxazoline)s
- 2.2 Thermoresponsive Polymers
- 2.3 Gels and Hydrogels
- 2.4 Swelling of Hydrogels
- 3. Characterization Methods
- 3.1 UV/VIS Spectroscopy
- 3.2 Thermal Analysis of Polymers (DSC/TGA)
- 3.3 Size Exclusion Chromatography
- 3.4 Atomic Force Microscopy
- 3.5 Surface Plasmon Resonance and Optical Waveguide Mode Spectroscopy
- 4. Results and Discussion
- 4.1 Polymerization Behavior of 2-Alkyl-2-Oxazolines
- 4.2 Preparation and Characterization of Thermoresponsive and Photocrosslinkable Poly(2-Alkyl-2-Oxazoline)-Based Hydrogel Films
- 4.3 Modification of Photocrosslinkable Poly(2-oxazoline)s via Azide–Alkyne Click Chemistry for the Preparation of Polymers with Improved Antifouling Properties
- 4.4 Published Application Examples of Photocrosslinkable Hydrogels
- 5. Experimental Part
- 5.1 Materials
- 5.2 Instrumentation
- 5.3 Synthesis of Monomers and Functionalization Units
- 5.4 Synthesis of Photocrosslinkable Poly(2-Alkyl-2-Oxazoline)s
- 5.5 Click Reaction of Photocrosslinkable and Azide Containing Poly(2-Alkyl-2-Oxazoline)s
- 5.6 Synthesis of Photocrosslinkable Poly(N-isopropylacrylamide)
- 5.7 Synthesis of Photocrosslinkable Carboxymethyl Dextran
- 5.8 Unsuccessful Synthesis
- 6. References
- 7. Appendix
- 7.1 Additional 1H- and 13C-NMR Spectra Monomers and Functionalization Units
- 7.2 Polymer Synthesis
- 7.3 Modification of Poly(2-isoPropyl-2-Oxazoline-co-2-(3-Azidopropyl)-2-Oxazoline-co-2-Benzophenone-2-Oxazoline) by Copper Catalyzed Huisgen 1,3-dipolar Cycloaddition
- 7.4 Synthesis 2-(prop-2-ynyloxy)propyl)-2-oxazoline
- 7.5 Additional UV/VIS Cloud Point Measurements
- 7.6 Additional AFM Data
- 7.7 SPR/OWS Spectra
- Publications, Book Sections and Poster Contributions