Integration event induced changes in recombinant protein productivity in Pichia pastoris discovered by whole genome sequencing and derived vector opti [...]
Schwarzhans, Jan Philipp ; Wibberg, Daniel ; Winkler, Anika ; Luttermann, Tobias ; Kalinowski, Jörn ; Friehs, KarlIn: Microbial Cell Factories, Jg. 15 H. 1A machine vision system for automated non-invasive assessment of cell viability via dark field microscopy, wavelet feature selection and classificati [...]
Wei, Ning ; Flaschel, Erwin ; Friehs, Karl ; Nattkemper, Tim WilhelmIn: BMC Bioinformatics, Jg. 9 H. 1, S. 449 ff.A Mitochondrial Autonomously Replicating Sequence from Pichia pastoris for Uniform High Level Recombinant Protein Production
Friehs, Karl ; Schwarzhans, Jan Philipp ; Luttermann, Tobias ; Wibberg, Daniel ; Winkler, Anika ; Hübner, Wolfgang ; Huser, Thomas ; Kalinowski, JörnIn: Frontiers in Microbiology, Jg. 8Non-canonical integration events in Pichia pastoris encountered during standard transformation analysed with genome sequencing
Schwarzhans, Jan Philipp ; Wibberg, Daniel ; Winkler, Anika ; Luttermann, Tobias ; Kalinowski, Jörn ; Friehs, KarlIn: Scientific Reports, Jg. 6 H. 1Parameters influencing the productivity of recombinant E. coli cultivations
Reardon, K. F. ; Friehs, Karl ; Aarts, R. (Hrsg.)Perceiving molecular evolution processes in Escherichia coli by comprehensive metabolite and gene expression profiling
Vijayendran, Chandran ; Barsch, Aiko ; Friehs, Karl ; Niehaus, Karsten ; Becker, Anke ; Flaschel, ErwinIn: GENOME BIOLOGY, Jg. 9 H. 4, S. R72 ff.Recombinant expression of an l-amino acid oxidase from the fungus Hebeloma cylindrosporum in Pichia pastoris including fermentation.
Heß, Marc ; Bloess, Svenja ; Risse, Joe Max ; Friehs, Karl ; Fischer von Mollard, GabrieleIn: MicrobiologyOpen, Jg. 9 H. 10Recombinant expression of Barnase in Escherichia coli and its application in plasmid purification
Shankar, Ram ; Schäffer, Nina ; Schmeer, Marco ; Friehs, Karl ; Risse, Joe Max ; Schleef, MartinIn: Microbial Cell Factories, Jg. 20Strategies for improving plasmid stability in genetically modified bacteria in bioreactors
Kumar, P. K. R. ; Maschke, H.-E. ; Friehs, Karl ; Schügerl, K.In: Trends in biotechnology, Jg. 9 H. 1, S. 279-284Systematic investigation into the clonal variability of the non-conventional yeast Pichia pastoris
Schwarzhans, Jan Philipp2017Unusual observations during construction of a new cloning vector providing lon gene expression in Escherichia coli
Friehs, Karl ; Bailey, J. E.In: Journal of Biotechnology, Jg. 9 H. 4, S. 305-316