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Bibliographic Metadata
- TitleNa,K-ATPase on a waveguide sensor : supramolecular assembly and side directed binding studies by surface-confined fluorescence
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- LanguageEnglish
- Document typeConference Proceedings
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Abstract
The functional assembly of FITC-Na,K-ATPase membrane fragments on a surface-modified Ta2O5 waveguide allows to investigate the directed binding of ligands by surface-confined fluorescence studies. The results allow to draw conclusions about the sidedness of interactions. The fluorescence intensity decrease observed upon the selective binding of K+ is attributed to its coordination to a site accessible from the former intracellular membrane side.
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