Giampa, Marco; Amundarain, María; Herrera, María Georgina; Tonali, Nicolo Michele; Dodero, Veronica Isabel: Implementing Complementary Approaches to Shape the Mechanism of α-Synuclein Oligomerization as a Model of Amyloid Aggregation. In: Molecules. Jg.27 H. 1. 2022
Inhalt
- Mechanisms of -Syn Aggregation In Vitro
- Monomer Aggregation Propensity Linked to Conformational Transition
- Monomer Aggregation in the Nucleation-Polymerization Theory
- Monomer Aggregation in Nucleation-Conversion-Polymerization Theory
- The Conformational Dynamics of -Syn Monomer Affect the Aggregation Process
- Meta-Stable -Syn Oligomers (Meta-S-Os)
- High and Low FRET Oligomers Subtypes
- Towards a Combination of All Types of Aggregation Models
- The Involvement of the Surface Hydrophobicity of Aggregates
- Tetramers of -Syn
- Liquid-Liquid Phase Separation
- Mechanisms of -Syn Aggregation in Biological Systems
- Conclusions and Perspectives
- References