Elsayed, Heba E.; Kamel, Reem A.; Ibrahim, Reham R.; Abdel-Razek, Ahmed S.; Shaaban, Mohamed A.; Frese, Marcel; Sewald, Norbert; Ebrahim, Hassan Y.; Moharram, Fatma A.: Cytotoxicity, Antimicrobial, and In Silico Studies of Secondary Metabolites From Aspergillus sp. Isolated From Tecoma stans (L.) Juss. Ex Kunth Leaves. In: Frontiers in Chemistry. Jg.9. 2021
Inhalt
- General Experimental Procedures
- Fungal Isolation and Fermentation
- Identification of the Isolated Fungal Strain
- Fungal Mass Cultivation
- Extraction and Isolation of the Secondary Metabolites
- Cell Lines and Culture Conditions
- MTT Cytotoxicity Assay
- Mode of Cell Death
- Standard Microbes, Antibiotics, and Culture Media
- Antimicrobial Susceptibility Test
- Determination of Minimum Inhibitory Concentrations
- Molecular Docking
- Results
- Arugosin C (1)
- Ergosterol (2)
- Iso-Emericellin (3)
- Sterigmatocystin (4) and Dihydrosterigmatocystin (5)
- Versicolorin B (6)
- Diorcinol (7)
- Discussion
- Conclusions
- Data Availability Statement
- Author Contributions
- Supplementary Material
- References