Junker, Nora; Goßmann, Toni: Adaptation-Driven Evolution of Sirtuin 1 (SIRT1), a Key Regulator of Metabolism and Aging, in Marmot Species. In: Frontiers in Ecology and Evolution. Vol.9. 2021, page 666564 et seq.
Content
- 2.1. Data Retrieval
- 2.2. Sequence Preparation and Selection Analysis
- 2.3. Selection Model Comparison
- 2.4. Structural Prediction
- 3. Results
- 3.1. Branch Test: Differences in Evolutionary Rates in Marmot Clade
- 3.2. Branch-Site Test: SIRT1 Repeatedly Evolved Under Positive Selection
- 3.3. Secondary Structure Prediction
- 4. Discussion
- Data Availability Statement
- Author Contributions
- Acknowledgments
- Supplementary Material
- References