Sielemann, Katharina ; Elbeck, Zaher; Gärtner, Anna; Brodehl, Andreas; Stanasiuk, Caroline; Fox, Henrik; Paluszkiewicz, Lech; Tiesmeier, Jens; Wlost, Stefan; Gummert, Jan; Albaum, Stefan ; Sielemann, Janik; Knöll, Ralph; Milting, Hendrik: Distinct Myocardial Transcriptomic Profiles of Cardiomyopathies Stratified by the Mutant Genes. In: Genes. Jg.11 H. 12. 2020
Inhalt
- Introduction
- Materials and Methods
- Patient Cohorts
- Sample Preparation and Sequencing Reaction
- Read Processing
- Data Normalisation, Principal Component Analysis and Determination of Differentially Expressed Genes
- K-Means Clustering
- GO Term and Pathway Analysis
- Prediction of Secreted Proteins, Regulatory Proteins and Potential Candidate Drug Targets
- Results
- GO Term and Pathway Analysis
- Prediction of Secreted Proteins, Regulatory Proteins and Potential Candidate Drug Targets
- Discussion
- GO Term and Pathway Analysis
- Prediction of Secreted Proteins, Regulatory Proteins and Potential Candidate Drug Targets
- Limitations of the Study
- Conclusions
- References