Kampa, Judith Martha; Kellner, Udo; Marsching, Christian; Ramallo Guevara, Carina; Knappe, Ulrich J; Sahin, Mikail; Giampa, Marco; Niehaus, Karsten; Bednarz, Hanna: Glioblastoma multiforme: Metabolic differences to peritumoral tissue and IDH-mutated gliomas revealed by mass spectrometry imaging.. In: Neuropathology : official journal of the Japanese Society of Neuropathology. Jg.40 H. 6. 2020, S. 546-558
Inhalt
- Human material
- RESULTS
- Antioxidants are enhanced in GBM
- Fatty acids show decreased intensities in tumor areas
- Alterations in compounds of purine and pyrimidine metabolism
- Further metabolites of the core metabolism are altered in GBM
- Comparison of GBMs with IDH-mutated gliomas
- DISCUSSION
- Antioxidants
- Fatty acids
- Purine and pyrimidine metabolites
- Lactate
- Glutamine and glutamate
- Citrate
- NAA
- IDH-mutated gliomas
- Conclusion
- ACKNOWLEDGMENTS
- DISCLOSURE
- REFERENCES