Fitzek, Elisabeth; Joardar, Archi; Gupta, Ramesh; Geisler, Matt: Evolution of Eukaryal and Archaeal Pseudouridine Synthase Pus10. In: Journal of Molecular Evolution. Jg.86 H. 1. 2018, S. 77-89
Inhalt
- Collection of Datasets
- Protein Alignment and Phylogenetic Analysis
- Annotation of Phylogenetic Trees
- Homology Modeling and Structural Superimposition
- Results
- Characterization of Key Conserved Structural Features of Pus10
- Presence, Absence, and Copy Number of Pus10 Orthologs in Whole Genomes
- Pus10 in Archaea
- Pus10 in Fungi
- Pus10 in Plants
- Pus10 in Animals and the Importance of THUMP Domain
- Discussion
- Evolutionary Resolution of Functional Redundancy in Pus10 and TruB
- Molecular Evolution of Pus10 in Eukaryota
- Conclusion
- Acknowledgements
- References