Schotter, Jörg: Development of a magnetoresistive biosensor for the detection of biomolecules. 2004
Inhalt
- Introduction
- Biochips: idea and applications
- Classification of biosensor types
- Magnetic biosensors
- Summery
- Preparation and analytical tools
- Film deposition
- Vacuum furnace
- Lithography
- Etching
- Energy dispersive X-ray sensor (EDX)
- Film thickness measurement system
- Atomic force microscope (AFM)
- Magneto-transport measurements
- Alternating gradient magnetometer (AGM)
- Magnetic markers
- Basic requirements for magnetic markers in biosensors
- Structure and common applications of magnetic microspheres
- Outlook: ferromagnetic nanoparticles as magnetic markers
- The surface of the magnetic biosensor
- GMR-type magnetic biosensor
- GMR theory
- Sensor layout and characteristics
- OOMMF model
- Detection of magnetic markers
- Reference signal
- Response to magnetic markers
- Dependence of the sensor signal on the marker coverage
- Conclusions
- TMR-type magnetic biosensor
- TMR theory
- Introduction
- Tunneling through a barrier
- Tunneling magnetoresistance
- Exchange bias
- Orange peel coupling
- Sensor layout
- Sensor characteristics
- OOMMF model
- Detection of magnetic markers
- Conclusions
- Comparison of GMR- and TMR-type magnetic biosensors
- DNA-detection and comparison to fluorescent method
- Summery and Outlook
- Bibliography
- Acknowledgements